𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cell Biology of HIV-1 Infection of Macrophages

✍ Scribed by Carter, Carol A.; Ehrlich, Lorna S.


Book ID
120004498
Publisher
Annual Reviews
Year
2008
Tongue
English
Weight
671 KB
Volume
62
Category
Article
ISSN
0066-4227

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We analyse mathematical models comparing the in vivo dynamics of macrophage-and T cell infection by HIV. Experiments suggest that HIV can only replicate in activated T cells whereas cell activation may not be required for successful replication in macrophages. These assumptions lead to fundamentally