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Cell-based screening assay for anti-inflammatory activity of bioactive compounds

✍ Scribed by Meijer, Kees; Vonk, Roel J.; Priebe, Marion G.; Roelofsen, Han


Book ID
125799117
Publisher
Elsevier Science
Year
2015
Tongue
English
Weight
648 KB
Volume
166
Category
Article
ISSN
0308-8146

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Huntington's disease (HD) is a late-onset, neurodegenerative disease for which there are currently no cures nor disease-modifying treatments. Here we report the identification of several potential anti-inflammatory targets for HD using an ex vivo model of HD that involves the acute transfection of h