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Cell-based models of sustained, interferon-sensitive hepatitis C virus genotype 1 replication

โœ Scribed by Yoichi Hiasa; Jason T. Blackard; Wenyu Lin; Yoshitaka Kamegaya; Norio Horiike; Morikazu Onji; Emmett V. Schmidt; Raymond T. Chung


Book ID
113767175
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
397 KB
Volume
132
Category
Article
ISSN
0166-0934

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To determine if the clearance of hepatitis C genotype 1 virus (HCV) is dependent on the dose of interferon alfa-2b (IFN-alpha2b), the acute clearance of HCV after a single dose of either 3, 5, or 10 mIU of IFN-alpha was compared in patients with chronic hepatitis C. HCV-RNA levels following IFN-alph