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Cell-Based Assays for High-Throughput Screening: Methods and Protocols

✍ Scribed by W. Frank An, Nicola J. Tolliday (auth.), Paul A. Clemons, Nicola J. Tolliday, Bridget K. Wagner (eds.)


Publisher
Humana Press
Year
2009
Tongue
English
Leaves
214
Series
Methods in Molecular Biology 486
Edition
1
Category
Library

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✦ Synopsis


As the use of high-throughput screening expands and creates more interest in the academic community, the need for detailed reference materials becomes ever more pressing. Cell-Based Assays for High-Throughput Screening: Methods and Protocols aims to fill an important part of this need by providing an easily accessible reference volume for cell-based phenotypic screening. Leading researchers in the field contribute state-of-the-art methods with actionable protocols covering four major areas of study: model biological systems, screening modalities and assay systems, detection technologies, and approaches to data analysis. Written in the highly successful Methods in Molecular Biologyβ„’ series format, each chapter includes a brief introduction to the subject, lists of necessary materials and reagents, step-by-step laboratory protocols, and a Notes section detailing tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and easy-to-use, Cell-Based Assays for High-Throughput Screening: Methods and Protocols presents an overview of relevant approaches, enabling the direct application of existing methods to new discoveries while also inspiring researchers to approach their screening projects in a conceptually modular fashion, enhancing the power to discover through new combinations of existing approaches.

✦ Table of Contents


Front Matter....Pages i-x
Back Matter....Pages 1-12
....Pages 13-27

✦ Subjects


Biochemistry, general; Combinatorial Libraries


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