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Cell based approaches for evaluation of drug-induced liver injury

✍ Scribed by Mhairi L. Greer; Jane Barber; Julie Eakins; J. Gerry Kenna


Book ID
108287616
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
965 KB
Volume
268
Category
Article
ISSN
0300-483X

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Distinguishing drug-induced liver injury (DILI) from idiopathic autoimmune hepatitis (AIH) can be challenging. We performed a standardized histologic evaluation to explore potential hallmarks to differentiate AIH versus DILI. Biopsies from patients with clinically well-characterized DILI [n = 35, in