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Cell age-specific vulnerability of neurons to anesthetic toxicity

✍ Scribed by Hofacer, Rylon D.; Deng, Meng; Ward, Christopher G.; Joseph, Bernadin; Hughes, Elizabeth A.; Jiang, Connie; Danzer, Steve C.; Loepke, Andreas W.


Book ID
120400255
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
693 KB
Volume
73
Category
Article
ISSN
0364-5134

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The intravenous, short-acting general anesthetic propofol was applied to three-dimensional (aggregating) cell cultures of fetal rat telencephalon. Both the clinically used formulation (Disoprivan@, ICI Pharmaceuticals, Cheshire, England) and the pure form (2,6-diisopropylphenol) were tested at two d