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Cell Adhesion Properties and Effects on Receptor-Mediated Insulin Endocytosis Are Independent Properties of pp120, a Substrate of the Insulin Receptor Tyrosine Kinase

✍ Scribed by Payal Soni; Khaled A. Al-Hosaini; Mats A. Fernström; Sonia M. Najjar

Book ID
115637416
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
119 KB
Volume
1
Category
Article
ISSN
1522-4724

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✍ Curtis V. Choice; Matthew N. Poy; Pietro Formisano; Sonia M. Najjar 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB 👁 3 views

pp120, a substrate of the insulin receptor tyrosine kinase, is a plasma membrane glycoprotein in the hepatocyte. It is expressed as two spliced isoforms differing by the presence (full length) or absence (truncated) of most of the intracellular domain including all phosphorylation sites. Because the