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Cell adhesion in tumor invasion and metastasis: loss of the glue is not enough

✍ Scribed by Ugo Cavallaro; Gerhard Christofori


Book ID
114222813
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
355 KB
Volume
1552
Category
Article
ISSN
0304-419X

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Over the past 10 years it has become apparent that invasion and metastasis are extremely complex processes; neoplastic cells must escape from the primary tumor, degrade the extracellular matrix, migrate to distant sites, arrest in the capillaries, and migrate through the basement membrane and underl