Cell adhesion biomaterial based on mussel adhesive protein fused with RGD peptide
β Scribed by Dong Soo Hwang; Sung Bo Sim; Hyung Joon Cha
- Book ID
- 103825452
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 844 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0142-9612
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## Abstract Adhesion of cells to a surface is a basic and important requirement in the fields of cell culture and tissue engineering. Previously, we constructed the cell adhesive, fpβ151βRGD, by fusion of the hybrid mussel adhesive protein, fpβ151, and GRGDSP peptide, one of the major cell adhesion
## Abstract Marrowβderived osteoblasts were cultured on poly(propylene fumarateβ__co__βethylene glycol) (P(PFβ__co__βEG)) based hydrogels modified in bulk with a covalently linked RGDS model peptide. A poly(ethylene glycol) spacer arm was utilized to covalently link the peptide to the hydrogel. Thr