Celiac disease transmitted by allogeneic non-T cell-depleted bone marrow transplantation
✍ Scribed by Bargetzi, M J; Schönenberger, A; Tichelli, A; Fried, R; Cathomas, G; Signer, E; Speck, B; Gratwohl, A
- Book ID
- 110010251
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 267 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0007-1188
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We investigated the adoptive transfer of immunity to herpes simplex virus (HSV) in 61 recipients of T-cell-depleted marrow allografts. Up to 3 months after bone marrow transplantation (BMT), high titres of HSV antibody (Ab) are passively acquired from blood products. This antibody has a half-life of
Recipients of allogeneic bone marrow transplantation are pancytopenic for several weeks and immunosuppressed for many months as a result of myeloablative therapy required to eliminate the basic disease and to prevent allograft rejection. After bone marrow transplantation, these patients remain profo