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Ceftobiprole: a novel cephalosporin with activity against Gram-positive and Gram-negative pathogens, including methicillin-resistant Staphylococcus aureus (MRSA)

✍ Scribed by April Barbour; Stephan Schmidt; Kenneth H. Rand; Hartmut Derendorf


Book ID
119260135
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
280 KB
Volume
34
Category
Article
ISSN
0924-8579

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We have shown that the intentional engineering of a natural product biosynthesis pathway is a useful way to generate stereochemically complex scaffolds for use in the generation of combinatorial libraries that capture the structural features of both natural products and synthetic compounds. Analysis