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C/EBP transcription factors expressed in the mammalian brain

✍ Scribed by R Ingrassia; T Gulotta; G Pollonini; M Ungari; F Facchetti; A Albertini; CM Alberini

Book ID
114303560
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
258 KB
Volume
90
Category
Article
ISSN
0928-4257

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The transcription factors CCAAT/enhancer binding protein (C/EBP)-␀ and -␦ are key regulators for the expression of the acute phase genes in the liver, such as complement component C3 and antichymotrypsin. In the brain, these acute phase proteins are produced in response to pro-inflammatory cytokines