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C/EBP- and Tat-mediated activation of the HIV-1 LTR in CD34+ hematopoietic progenitor cells

โœ Scribed by Shane Quiterio; Christian Grant; Tricia H. Hogan; Fred C. Krebs; Brian Wigdahl


Book ID
117575544
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
408 KB
Volume
57
Category
Article
ISSN
0753-3322

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## Abstract Transcription of the HIVโ€1 genome is a complex event that requires functional and physical communication of cellular proteins that recognize the LTR sequence with viral proteins, most notably, Tat. Moreover, studies have revealed the ability of Tat to induce transcription of a variety o