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cDNA sequence of Aldgh, the mouse homolog of the X-linked adrenoleukodystrophy gene

โœ Scribed by C. -O. Sarde; J. Thomas; H. Sadoulet; J. -M. Garnier; J. -L. Mandel

Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
579 KB
Volume
5
Category
Article
ISSN
0938-8990

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โœ Sonja Forss-Petter; Hauke Werner; Johannes Berger; Hans Lassmann; Brunhilde Molz ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 1021 KB

In its severe form, X-linked adrenoleukodystrophy (ALD) is a lethal neurologic disease of children, characterized by progressive cerebral demyelination and adrenal insufficiency. Associated with a biochemical defect of peroxisomal โค-oxidation, very long-chain fatty acids (VLCFA) build up in tissues