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cDNA sequence and differential expression of the mouse Ca2+/calmodulin-dependent protein kinase IV gene

โœ Scribed by David A. Jones; John Glod; Donna Wilson-Shaw; William E. Hahn; James M. Sikela

Book ID
115925187
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
608 KB
Volume
289
Category
Article
ISSN
0014-5793

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## Abstract Ca^2+^ influx through Lโ€type voltageโ€gated Ca^2+^ channels (Lโ€VSCC) is required for K^+^โ€induced somatostatin (SS) mRNA. Increase in intracellular Ca^2+^ concentration leads to the activation of cyclic AMPโ€responsive element binding protein (CREB), a key regulator of SS gene transcripti