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cDNA array technology in melanoma: An overview

✍ Scribed by Alfonso Baldi; Daniele Santini; Antonio De L uca; Marco G. Paggi

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
85 KB
Volume
196
Category
Article
ISSN
0021-9541

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✦ Synopsis

Abstract

Genetic aberrations, mostly resulting in changes in gene expression, are critical events in cancer onset and progression. The advent of the cDNA array technology allows the screening and the efficient measurement of expression of thousands genes simultaneously in a wide spectrum of experimental and clinical models. This genomic scale approach is being currently used to obtain global views of human cancer gene expression and to identify genetic markers that might be important for diagnosis, prognosis, and therapy. This review discusses some recent findings obtained by means of cDNA arrays investigating the human melanoma. J. Cell. Physiol. 196: 219–223, 2003. Β© 2003 Wiley‐Liss, Inc.

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Edited By Uwe Marx And Volker Sandig. Includes Bibliographical References And Index. Also Available In An Electronic Version. Mode Of Access: World Wide Web.