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CDKN2A is not the principal target of deletions on the short arm of chromosome 9 in neuroendocrine (Merkel cell) carcinoma of the skin

✍ Scribed by Anthony L. Cook; Pamela M. Pollock; John Welch; Michael D. Walsh; Rayleen V. Bowman; Kathryn C. Baumann; Nicholas K. Hayward; J. Helen Leonard

Publisher: John Wiley and Sons
Year: 2001
Tongue: French
Weight: 637 KB
Volume: 93
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.1352

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Little is known about the biology of Merkel cell carcinoma (MCC), also called small cell carcinoma of the skin. MCC has similarities with small cell lung cancer (SCLC): both are neuroendocrine malignancies with early metastasis t o distant sites and a poor prognosis. Small cell lung cancer biopsies