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Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint

✍ Scribed by Zhang, Nianxiang; Kaur, Ramandeep; Akhter, Shamima; Legerski, Randy J


Book ID
109851278
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
674 KB
Volume
10
Category
Article
ISSN
1469-221X

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## Abstract To study the putative role of de novo synthesis of glutathione (GSH) in the regulation of the cell cycle, we exposed NIH‐3T3 cells to buthionine sulfoximine (BSO) and analysed cell cycle kinetics with continuous bromodeoxyuridine (BrdU) labeling and bivariate Hoechst 33258/ethidium brom