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CD8+ T-cells from HIV-infected patients can either augment or abrogate HIV-specific lymphoproliferation

✍ Scribed by S.J.D. Bell; D.A. Cooper; B.E. Kemp; R.R. Doherty; R. Penny


Book ID
118375478
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
741 KB
Volume
64
Category
Article
ISSN
1090-2341

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## Abstract Chronically HIV‐1‐infected patients fail to contain their viremia despite high frequencies of HIV‐1‐specific, IFN‐γ‐producing CD8^+^ T cells. However, these cells are known to exhibit both phenotypic and functional defects. We tested if mature dendritic cells (DC) could correct defectiv