Notch1 expression on T cells is not requ
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Fabienne Tacchini-Cottier; Cindy Allenbach; Luc A. Otten; Freddy Radtke
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Article
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2004
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John Wiley and Sons
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English
⚖ 225 KB
## Abstract Notch1 proteins are involved in binary cell fate decisions. To determine the role of Notch1 in the differentiation of CD4^+^ Th1 versus Th2 cells, we have compared T helper polarization __in vitro__ in naive CD4^+^ T cells isolated from mice in which the N1 gene is specifically inactiva