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CD79B and MYD88 mutations in diffuse large B-cell lymphoma

โœ Scribed by Kim, Yuil; Ju, Hyunjeong; Kim, Dong Hoon; Yoo, Hae Yong; Kim, Suk Jin; Kim, Won Seog; Ko, Young Hyeh

Book ID
122331552
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
438 KB
Volume
45
Category
Article
ISSN
1532-8392

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โœ Schuetz, J M; Johnson, N A; Morin, R D; Scott, D W; Tan, K; Ben-Nierah, S; Boyle ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 400 KB

BCL2 is deregulated in diffuse large B-cell lymphoma (DLBCL) by the t(14;18) translocation, gene amplification and/or nuclear factor-kB signaling. RNA-seq data have recently shown that BCL2 is the most highly mutated gene in germinal center B-cell (GCB) DLBCL. We have sequenced BCL2 in 298 primary D