CD62, thromboxane B2, and beta-thromboglobulin: A comparison between different markers of platelet activation after contact with biomaterials
✍ Scribed by Cenni, E. ;Granchi, D. ;Verri, E. ;Cavedagna, D. ;Gamberini, S. ;Falsone, G. ;Pizzoferrato, A.
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 96 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0021-9304
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✦ Synopsis
The authors examined the modifications of some min of contact, but a significant increase in CD62 was demarkers of platelet activation after contact with biomaterials.
tected. After 30 min a significant increase in platelet adhesion Glycoprotein GMP-140 (CD62) was evaluated by flow cy-as well as the release of -TG and TXB 2 were noted. The tometry; -thromboglobulin (-TG) and thromboxane B 2 increase was lower than that observed for uncoated PET, (TXB 2 ) were determined by radioimmunoassay. Polyethylene and after 30 min of contact with PC the increase no longer terephthalate (PET) induced a remarkable platelet adhesion was observed.