CD59 blockade on human CD4+ T cells leads to marked enhancement of antigen-specific responses
✍ Scribed by Sivasankar Baalasubramanian; Paula Longhi; Kathleen Gallagher; Gareth Betts; B. Paul Morgan; Andrew Godkin; Awen Gallimore
- Book ID
- 116757073
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 69 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0161-5890
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Spontaneous tumors frequently express antigens that can be recognized by the immune system but nevertheless manage to evade immune surveillance. To better understand the mechanism of evasion, we followed CD8 and CD4 T cells reacting against a subcutaneously growing tumor, modified to ex
## Abstract Naturally occurring CD4^+^ regulatory T cells can be identified on the basis of expression of CD25 and suppression of T cell responses __in vitro__ after TCR triggering. Here, we demonstrate that a CD134^+^ subset of CD4^+^CD25^+^ T cells in naive rats suppresses antigen‐specific T cell