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CD4+CD25+FoxP3+ T lymphocytes fail to suppress myelin basic protein-induced proliferation in patients with multiple sclerosis

✍ Scribed by Manoj Kumar; Norman Putzki; Volker Limmroth; Ralph Remus; Monika Lindemann; Dietmar Knop; Norbert Mueller; Cornelia Hardt; Ernst Kreuzfelder; Hans Grosse-Wilde


Book ID
113729940
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
215 KB
Volume
180
Category
Article
ISSN
0165-5728

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## Abstract Accumulating evidence indicates an immunosuppressive role for CD4^+^CD25^+^ regulatory T cells (Tregs) in autoimmune diseases. Although an impaired Treg function in patients with relapsing‐remitting multiple sclerosis (RR‐MS) has been reported recently, no information is available so fa