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CD4+CD25+ regulatory/suppressor T cells prevent allogeneic fetus rejection in mice

✍ Scribed by Guillaume Darasse-Jèze; David Klatzmann; Frédéric Charlotte; Benoît L. Salomon; José L. Cohen

Book ID
108152263
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
126 KB
Volume
102
Category
Article
ISSN
0165-2478

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CD4 ؉ CD25 ؉ regulatory T cells (Treg) are important mediators of peripheral immune tolerance; however, whether Treg participate also in hepatic immune tolerance is not clear. Therefore, we tested the potential of Treg to suppress stimulation of CD4 ؉ T cells by liver sinusoidal endothelial cells (L