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CD4+CD25+ Regulatory T Cells Suppress the Developmental Pathway From TH17 to Alternative TH1 Cells via TH17/TH1 and TH1-Like Cells

✍ Scribed by Tomohisa Sujino; Takanori Kanai; Yuuichi Ono; Yohei Mikami; Atsushi Hayashi; Tomomitsu Doi; Katsuyoshi Matsuoka; Tadakazu Hisamatsu; Hiromasa Takaishi; Haruhiko Ogata; Akihiko Yoshimura; Toshifumi Hibi


Book ID
119432456
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
141 KB
Volume
140
Category
Article
ISSN
0016-5085

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TIM-3 is expressed on activated human CD
✍ William D. Hastings; David E. Anderson; Nasim Kassam; Ken Koguchi; Edward A. Gre πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 545 KB

## Abstract TIM‐3 is a molecule selectively expressed on a subset of murine IFN‐γ‐secreting T helper 1 (Th1) cells but not Th2 cells, and regulates Th1 immunity and tolerance __in vivo__. At this time little is known about the role of TIM‐3 on human T cells. To determine if TIM‐3 similarly identifi