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CD4+CD25+ regulatory T cell-mediated changes in the expression of endocytic receptors and endocytosis process of human dendritic cells

✍ Scribed by Ana-Maria Navarrete; Sandrine Delignat; Jean-Luc Teillaud; Srini V. Kaveri; Sébastien Lacroix-Desmazes; Jagadeesh Bayry

Book ID: 116963511
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 280 KB
Volume: 29
Category: Article
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2011.01.095

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The transcription factor FOXP3 plays a key role in CD4 + CD25 + regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little is known about the frequency of CD4 + CD25 + cells that express FOXP3 protein