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CD4+CD25– effector T-cells inhibit hippocampal long-term potentiation in vitro

✍ Scribed by Gil M. Lewitus; Julia Zhu; Huangui Xiong; Richard Hallworth; Jonathan Kipnis


Book ID
109026122
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
569 KB
Volume
26
Category
Article
ISSN
0953-816X

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We have further characterized the in vitro phenotype and function of anergic and suppressive CD4(+)25(+) T cells. Following TCR ligation, DO.11.10 CD4(+)25(+) T cells suppress the activation of OT-1 CD8(+)25(-) T cells in an antigen nonspecific manner. Although suppression was seen when using a mixt