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CD44 variant 6 (CD44v6) expression is associated with poor prognosis in superficial esophageal adenocarcinoma (SADC)

✍ Scribed by Ormsby, AH; Rice, TW; Rybicki, LA; Goldblum, JR

Book ID: 122417975
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 180 KB
Volume: 114
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(98)82698-X

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CD44 is a cell surface glycoprotein with a number of isoforms generated by alternative splicing of ten 'variant' exons in humans. Variant exon 6-containing isoforms of CD44 (CD44v6) have been implicated in the metastatic potential of rat carcinoma cell lines. Human homologues of CD44v6 are expressed