CD44 is required for the migration of transplanted oligodendrocyte progenitor cells to focal inflammatory demyelinating lesions in the spinal cord

Inflammation promotes survival and migra

Inflammation promotes survival and migration of the CG4 oligodendrocyte progenitors transplanted in the spinal cord of both inflammatory and demyelinated EAE rats

✍ A. Tourbah; C. Linnington; C. Bachelin; V. Avellana-Adalid; H. Wekerle; A. Baron 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 606 KB

Oligodendrocyte progenitor CG4 cells were labeled with bisbenzimide and transplanted in the lumbar spinal cord of rats 15 to 17 days prior to the induction of experimental autoimmune encephalomyelitis (EAE). EAE was induced by immunization with the encephalitogenic peptide of myelin basic protein (a