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CD44 and β1 Integrin Mediate Ovarian Carcinoma Cell Adhesion to Peritoneal Mesothelial Cells

✍ Scribed by Khashayar Lessan; Dean J. Aguiar; Theodore Oegema; Lisa Siebenson; Amy P.N. Skubitz


Book ID
117022693
Publisher
American Society for Investigative Pathology
Year
1999
Tongue
English
Weight
219 KB
Volume
154
Category
Article
ISSN
0002-9440

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Epithelial ovarian carcinoma, the leading cause of gynecologic cancer death, is characterized by widespread intra-abdominal metastases mediated primarily by surface shedding of tumor cells and peritoneal implantation. Whereas hematogenous metastasis is known to involve cellular adhesion, extracellul