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CD40L-expressing CD8 T cells prime CD8α+ DC for IL-12p70 production

✍ Scribed by Kok Loon Wong; Fei Chuin Lew; Paul A. MacAry; David M. Kemeny

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
431 KB
Volume
38
Category
Article
ISSN
0014-2980

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## Abstract The potent innate cytokines IL‐12 and IL‐18 are considered to be important antigen‐independent mediators of IFN‐γ production by NK cells and T lymphocytes. The present analysis addresses the physiological role of IL‐12 and IL‐18 in the generation of virus‐specific CD8^+^ T cells. Both w