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CD40/CD40L interaction regulates CD4+CD25+ T reg homeostasis through dendritic cell-produced IL-2

✍ Scribed by Cristiana Guiducci; Barbara Valzasina; Heidrun Dislich; Mario P. Colombo

Book ID: 102168692
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 345 KB
Volume: 35
Category: Article
ISSN: 0014-2980
DOI: 10.1002/eji.200425810

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## Abstract ## Objective Stromal cell–derived factor 1 (SDF‐1) is a potent chemoattractant for memory T cells in inflamed rheumatoid arthritis (RA) synovium. This study was undertaken to investigate the effect of interleukin‐17 (IL‐17) and CD40–CD40L interaction on SDF‐1 production in RA fibroblas