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CD40 cross-linking enhances the immunogenicity of Burkitt's-lymphoma cell lines

โœ Scribed by Teresa Frisan; Daria Donati; Laszlo Cervenak; Julia Wilson; Maria Grazia Masucci; Maria Teresa Bejarano


Publisher
John Wiley and Sons
Year
1999
Tongue
French
Weight
190 KB
Volume
83
Category
Article
ISSN
0020-7136

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CD40 is a membrane glycoprotein expressed on normal and neoplastic B lymphocytes. Stimulation through CD40 regulates important cellular functions, but the effects depend on its membrane density. While extensive studies have characterized CD40 in non-Hodgkin lymphomas of immunocompetent individuals,