✦ LIBER ✦

CD40 and epithelial cells: across the great divide

✍ Scribed by Lawrence S Young; Aristides G Eliopoulos; Neil J Gallagher; Chris W Dawson

Book ID: 104298977
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 434 KB
Volume: 19
Category: Article
ISSN: 0167-5699
DOI: 10.1016/s0167-5699(98)01340-1

No coin nor oath required. For personal study only.

✦ Synopsis

The widespread expression of CD40 in normal epithelial cells and carcinoma cells suggests that this receptor has important, additional influences beyond that of regulating immune responses. Here, Lawrence Young and colleagues discuss the effect of CD40 ligation on epithelial cells and consider the role of this pathway in the pathogenesis and treatment of carcinomas.

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