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CD4+ T Cells in Lymph Nodes of UVB-Irradiated Mice Suppress Immune Responses to New Antigens Both In Vitro and In Vivo

โœ Scribed by Gorman, Shelley; Tan, Jamie W-Y; Yerkovich, Stephanie T; Finlay-Jones, John J; Hart, Prue H


Book ID
110049675
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
225 KB
Volume
127
Category
Article
ISSN
0022-202X

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Identification of a CD4+CD25+ T cell sub
โœ Estherโ€„N.โ€„M. Nolte-โ€˜t Hoen; Josรฉeโ€„P.โ€„A. Wagenaar-Hilbers; Elmiekeโ€„P.โ€„J. Boot; Ch ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 347 KB ๐Ÿ‘ 1 views

## Abstract Naturally occurring CD4^+^ regulatory Tโ€„cells can be identified on the basis of expression of CD25 and suppression of Tโ€„cell responses __in vitro__ after TCR triggering. Here, we demonstrate that a CD134^+^ subset of CD4^+^CD25^+^ Tโ€„cells in naive rats suppresses antigenโ€specific Tโ€„cell