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CD4+ T cells in antitumor immunity: utility of an Ii-Key HER2/neu hybrid peptide vaccine (AE37)

✍ Scribed by Mittendorf, Elizabeth A; Holmes, Jarrod P; Murray, James L; von Hofe, Eric; Peoples, George E


Book ID
115453159
Publisher
Informa plc
Year
2008
Tongue
English
Weight
318 KB
Volume
9
Category
Article
ISSN
5847-4714

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## Abstract The Ii‐Key fragment from the MHC class II‐associated invariant chain (or Ii protein) has been shown to facilitate direct charging of MHC class II epitopes to the peptide binding groove. The purpose of the present study was to test the potential of a series of Ii‐Key/HER‐2__/neu__(776–79