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CD4+ T Cells and Cytokines in the Pathogenesis of Acquired Myasthenia Gravis

✍ Scribed by Bianca M. Conti-Fine; Monica Milani; Wei Wang

Book ID
111483706
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
591 KB
Volume
1132
Category
Article
ISSN
0890-6564

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Myasthenia gravis (MG) and its animal model experimental autoimmune myasthenia gravis (EAMG) are caused by autoantibodies against nicotinic acetylcholine receptor (AChR) in skeletal muscle. The production of anti-AChR antibodies is mediated by cytokines produced by CD4+ and CD8+ T helper (Th) cells.