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CD4+ T-cell activation for immunotherapy of malignancies using Ii-Key/MHC class II epitope hybrid vaccines

✍ Scribed by Minzhen Xu; Nikoletta L. Kallinteris; Eric von Hofe


Book ID
116964790
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
260 KB
Volume
30
Category
Article
ISSN
0264-410X

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CIITA-driven MHC-II positive tumor cells
✍ Valeria Frangione; Lorenzo Mortara; Patrizia Castellani; Andrea De Lerma Barbaro πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 987 KB

## Abstract In our study, we have investigated whether tumors of distinct histological origin can be rejected if expressing CIITA‐driven MHC class II molecules. Moreover, we assessed whether antitumor lymphocytes generated by this approach could be used as an immunotherapeutic tool for established