Circulating CD3+ T lymphocytes that express neither the CD4 nor CD8 surface molecules (double-negative T lymphocytes) are phenotypically and functionally distinct from single-positive CD3+CD4+ and CD3+CD8+ lymphocytes and are thought to represent a distinct T-cell lineage. The presence of low number
CD4 expression on liver sinusoidal cells: Enhancement in liver transplant rejection
โ Scribed by Giorgio Senaldi; Giorgina Mieli-Vergani; Bernard Portmann; Alex P. Mowat; Diego Vergani
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 96 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0270-9139
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The mechanisms by which T cells contribute to the hepatic inflammation during antigen-independent ischemia/reperfusion (I/R) are not fully understood. We analyzed the recruitment of T cells in the postischemic hepatic microcirculation in vivo and tested the hypothesis that T cells interact with plat
## Background: Regulatory T-cells (Treg) are natural suppressors of autoimmunity. Previous studies indicate that immunosuppressive drugs, especially calcineurin-inhibitors, may interfere with Treg homeostasis. Inflammatory bowel disease (IBD) can relapse or develop de novo after liver transplantati