๐”– Bobbio Scriptorium
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CD4-BFFI: A novel, bifunctional HIV-1 entry inhibitor with high and broad antiviral potency

โœ Scribed by Andreas Jekle; Eugene Chow; Erhard Kopetzki; Changhua Ji; Mei Jun Yan; Rosa Nguyen; Surya Sankuratri; Nick Cammack; Gabrielle Heilek

Book ID
113458128
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
643 KB
Volume
83
Category
Article
ISSN
0166-3542

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A new hydroxyethylamine class of inhibitors was designed combining features from our clinical candidate, L-735.524, along with small heterocvclic PGaands develoDed in these laboratories. Hiahlv notent inhibitors possessing sub&omolar IC5O's have beenid&ified, whi<h exhibit good antiviral pott& h cel