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CD28 regulates proximal T cell signaling events

✍ Scribed by Pietro G. Andres; Kimberly C. Howland; Abul K. Abbas; Mathew Krummel

Book ID: 119427625
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 169 KB
Volume: 124
Category: Article
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(03)80767-9

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## T cell receptodCD3 and CD28 use distinct intracellular signaling pathways* Ligation of the T cell membrane antigen CD28 strongly enhances cytokine secretion in humanT lymphocytes that are activated viaTcell receptor (TcR)/CD3 or CD2 molecules.This study was undertaken to investigate whether, as