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CD27+ Developing B Cells are Common in Human Fetal Liver

✍ Scribed by McWilliams, L.M.; Su, K.Y.; Liang, X.; Floyd, S.; Amos, J.; Moody, M.; Kelsoe, G.; Kuraoka, M.


Book ID
119286519
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
41 KB
Volume
129
Category
Article
ISSN
1097-6825

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B cell chronic lymphocytic leukemia (B-CLL) is a disease of the elderly and is characterized by a malignant clone of CD5+ B cells. In old mice, clonal expansions of CD5+ B cells are a common feature, and these animals frequently develop B-CLL. To investigate whether clonal expansion of CD5+ B cells