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CD25+CD8+, CLA+CD4+, CD11a+ CD4+ and CD11a+ CD8+ T Cell Counts Are Elevated in the Blood of Brazilian Patients

✍ Scribed by C. Porto Ferreira; A. Gomes da Silva; C.J. Martins; A.M. Da-Cruz


Book ID
119628385
Publisher
Elsevier Science
Year
2011
Tongue
Spanish
Weight
50 KB
Volume
102
Category
Article
ISSN
0001-7310

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CD4, CD8 and the role of CD45 in T-cell
✍ Jeffrey A. Ledbetter; Julie P. Deans; Alejandro Aruffo; Laura S. Grosmaire; Stev πŸ“‚ Article πŸ“… 1993 πŸ› Elsevier Science 🌐 English βš– 1009 KB

CD4, CD8 and CD45 regulate the coupling of the T-cell receptor complex (CD3-TCR) to tyrosine kinase activation and phosphorylation of key substrates such as phospholipase C gamma 1. CD4 and CD8 contribute to activation signals through their cytoplasmic association with p56lck. Expression of the zeta