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CD200Fc fusion protein alleviates beta amyloid-induced glial-activation and neurodegeneration in vitro and in vivo

✍ Scribed by Cowley, Thelma R.; Miller, Anne-Marie; Piazza, Alessia; Downer, Eric J.; Lynch, Marina A.


Book ID
122947171
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
37 KB
Volume
5
Category
Article
ISSN
1552-5260

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## Abstract The inflammatory responses in Alzheimer's disease (AD) and prion‐related encephalopathies (PRE) are dominated by microglia activation. Several studies have reported that the amyloid‐beta (AΞ²) peptides, which are associated with AD, and the pathogenic isoform of prion protein (PrP^Sc^) h