CD1d antigen presentation: treats for NKT cells
β Scribed by Godfrey, Dale I; McCluskey, James; Rossjohn, Jamie
- Book ID
- 109921589
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 197 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1529-2908
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π SIMILAR VOLUMES
Natural killer T (NKT) cells are a subset of lymphocytes that express cell surface molecules of both conventional T cells and natural killer cells and share the features of both innate and adaptive immune cells. NKT cells have been proposed to make both protective and pathogenic contributions to inf
CD1d-reactive NKT cells are required for the development of antigen-specific T regulatory (Tr) cells responsible for mediating systemic tolerance induced through an immune privileged site such as the eye. The aim of this study was to elucidate the cellular source of CD1d needed for NKT cell activati