CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia

✍ Scribed by Brentjens, R. J.; Davila, M. L.; Riviere, I.; Park, J.; Wang, X.; Cowell, L. G.; Bartido, S.; Stefanski, J.; Taylor, C.; Olszewska, M.; Borquez-Ojeda, O.; Qu, J.; Wasielewska, T.; He, Q.; Bernal, Y.; Rijo, I. V.; Hedvat, C.; Kobos, R.; Curran, K.; Steinherz, P.; Jurcic, J.; Rosenblat, T.; Maslak, P.; Frattini, M.; Sadelain, M.

• Book ID: 120068457
• Publisher: American Association for the Advancement of Science
• Year: 2013
• Tongue: English
• Weight: 141 KB
• Volume: 5
• Category: Article
• ISSN: 1946-6234
• DOI: 10.1126/scitranslmed.3005930

✦ Synopsis

Five adults with chemotherapy-refractory B-ALL were induced into molecular remissions after treatment with CD19 CAR-targeted T cells.