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✦   LIBER   ✦

CD133, One of the Markers of Cancer Stem Cells in Hep-2 Cell Line

✍ Scribed by Liang Zhou; Xudong Wei; Lei Cheng; Jie Tian; Jack J. Jiang

Book ID
110088383
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
441 KB
Volume
117
Category
Article
ISSN
0023-852X

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Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide. CD133, a transmembrane glycoprotein, is an important cell surface marker for both stem cells and cancer stem cells in various tissues including liver. CD133 expression has been recently linked to poor prognosis

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## Dear Editor, We read the comments of Angela Gradilone et al. on our article ''Isolation and characterization of tumorigenic extrahepatic cholangiocarcinoma cells with stem cell-like properties.'' The authors concluded that CD133 and ALDH1 are two other molecular markers of putative cancer stem