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CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges

✍ Scribed by Grosse-Gehling, Philipp; Fargeas, Christine A; Dittfeld, Claudia; Garbe, Yvette; Alison, Malcolm R; Corbeil, Denis; Kunz-Schughart, Leoni A

Book ID: 118765513
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 393 KB
Volume: 229
Category: Article
ISSN: 0022-3417
DOI: 10.1002/path.4086

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## Abstract ## Background Mounting evidence suggests that most tumors consist of a heterogeneous population of cells with a subset population that has the exclusive tumorigenic ability. They are called cancer stem cells (CSCs). CSCs can self‐renew to generate additional CSCs and also differentiate