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CD127 immunophenotyping suggests altered CD4+ T cell regulation in primary progressive multiple sclerosis

✍ Scribed by Fiona C. McKay; Louisa I. Swain; Stephen D. Schibeci; Justin P. Rubio; Trevor J. Kilpatrick; Robert N. Heard; Graeme J. Stewart; David R. Booth


Book ID
116614132
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
425 KB
Volume
31
Category
Article
ISSN
0896-8411

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Circulating lymphocyte subpopulations defined by anti-CD45 and other more common T-cell-specific monoclonal antibodies were analysed in 77 patients with multiple sclerosis and 38 healthy controls. A selective decrease of CD4+CD45+ cell percentages and absolute numbers in chronic-progressive patients